Catalytic Enantioselective Ynamide Additions to Isatins: Concise Access to Oxindole Alkaloids
نویسندگان
چکیده
منابع مشابه
Catalytic Enantioselective Addition of Me2Zn to Isatins
Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several chemical transformations were performed with the 3-hydroxy-2-oxindoles obtained.
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2019
ISSN: 1433-7851
DOI: 10.1002/anie.201814074